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Its a prescription medicine and not an over the counter (OTC) product. If your symptoms do not improve within a few days, or if they become worse, check with your doctor. Key highlights of Combantrin A 400 MG Tablet. This is a CTA link. killing it. However, your doctor or pharmacist may have suggested a different schedule that is more appropriate for you. Pinworms may be easily passed from one person to another, especially among persons in the same household. Combantrin A inhibits polymerization of tubulin causes loss of cytoplasmic microtubules that leads to impaired uptake of glucose, depletes glycogen stores, degenerative change in the endoplasmic reticulum and mitochondria & decrease production of ATP. Know uses side effects dosage contraindications substitutes benefit interactions purpose drug interactions precautions warnings etc. . Anthelmintics are used in the treatment of worm infections. When they gave the second dose, they figured out that the immune response got better with the second dose. Combantrin A 400mg Tablet should be taken only when prescribed by the doctor. These tests carried out in mice and dogs showed the compound to be effective against intestinal nematodes representative of those found in humans, such as pinworms, large roundworms and hookworms. Combantrin A should be immediately discontinued if acute renal failure due to hypersensitivity reaction is suspected. (Rigorous cleaning of living quarters and clothing to destroy helminthic ova will help prevent reinfection.). Consult a doctor before taking any medicines. No special procedures, such as fasting or purging, are required. Combantrin A is time tested and clinically proven well tolerated drug. We don't support your browser. Pyrantel may be taken with milk or fruit juice. This medication should be consumed, until the complete eradication of the disease. Use a specially marked measuring spoon or other device to measure each dose accurately. Keep away from light and out of the reach of children. see full prescribing information from innovator It also acts against larval and adult stages. Wearing tight underpants both day and night. If you forget a dose of Combantrin A 400mg Tablet, take it as soon as you remember. Pyrantel pamoate treatment for all family members is recommended. Cattle & Buffalo: 7.5-10 mg/kg body weight or 14 bolus for 30-40 kg body weight, 12 bolus for 60-80 kg body weight & 1 boli for 120-160 kg body weight. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Item. What are the contraindications of Combantrin A 400 MG Tablet ? This medication is typically used to eliminate intestinal worms. Let each vial stand at room temperature for 15 minutes before administering. Copyright 2023 IBM Watson Health. Wash hands and fingernails often, especially before eating and after using the toilet. 12's. Type. If you have any questions about this, check with your doctor. They do not kill eggs or immature worms and will not protect you from contracting Pinworms/Threadworms if you are exposed to them again. Therefore, all household members may have to be treated at the same time to prevent their infection or reinfection. If your dose is different, do not change it unless your doctor tells you to do so. 1 chocolate square 100mg twice each day for 3 consecutive days. Visual appearance Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. To learn more about the lifecycle of threadworms see our worm treatment page. Do not skip doses and finish the prescribed course, even if you start to feel better. India's only LegitScript and ISO/ IEC 27001 certified online healthcare platform. As cytoplasmic microtubules are critical in promoting glucose uptake in larval and adult stages of the susceptible parasites, the glycogen stores of the parasites are depleted. 2023 Lybrate, Inc. All rights reserved. For informational purposes only. Combantrin A 400mg Tablet may be taken with or without food, but it is better to take it at a fixed time. It should only be used in the treatment of echinococcosis if there is constant medical supervision with regular monitoring of serumtransaminase concentrations and of leucocyte and platelet counts. The double dose can give unwanted side effects, so be careful. Studies have not been done in pregnant women. You can also order Ayurvedic, Homeopathic and other Over-The-Counter (OTC) health products. Directions: Each flavored chewable contains 30 mg of Combantrin pamoate and 30 mg of praziquantel. It also treats hydatid disease, pinworm disease (intestinal infection), ascariasis (gastrointestinal infection), filariasis (affecting the lymph nodes and vessels) and others. It is taken as a single dose and may need to be repeated in two to three weeks. However, pyrantel is not recommended during breast-feeding. The vaccines . It is used for treating several diseases caused by an infestation of parasitic worms. Pyrantel has not been reported to cause problems in nursing babies. If you take it on an empty stomach, it might upset the stomach. 2 years or older: 100 mg orally twice a day (morning and evening) for 3 consecutive days 500 mg chewable tablet: 1 year or older: 500 mg orally once as a single dose Comments: If the patient is not cured 3 weeks after treatment with the 100 mg chewable tablet, a second course of therapy is advised. This medication may be taken with or without food. Be sure that any discarded medicine is out of the reach of children. Pinworms may be easily passed from one person to another, especially among persons in the same household. Combantrin A 400mg Tablet should not be given to patients with known allergy to any other ingredients of this medicine, or any other similar medicines like mebendazole or thiabendazole, in the past. Combantrin A is also used to associated treatment for these conditions: Ascariasis, Hookworm Infection, Hydatid disease caused by Echinococcus granulosus, Neurocysticercosis caused by Taenia solium, Other specified protozoal diseases. However, because pharmacokinetic interactions involving grapefruit juice are often subject to a high degree of interpatient variability, the extent to which a given patient may be affected is difficult to predict. You may experience loss of hair (reversible); dizziness or headaches (use caution when driving or engaging in tasks that require alertness until response to drug is known). Combantrin A 400mg Tablet is used for the treatment of infections caused by helminths (worms) like pin worms/thread worms, roundworms, hookworms, whip worms, liver flukes and tapeworm infections. 11 mgkg base orally once a day for 3 days Maximum dose. Familiprix inc. and proprietary pharmacists affiliated with Familiprix do not engage in any way by making this information available on this website. For patients taking pyrantel oral suspension : To help clear up your infection completely, take this medicine exactly as directed by your doctor. It should not be used in pregnant women, unless in the judgment of the physician it is deemed essential for the welfare of the patient. Combantrin A 400 MG Tablet is generally prescribed to treat diseases like neurocysticercosis affecting the brain muscles and other tissues and giardiasis intestinal infection. Combantrin A 400 MG Tablet is an antiparasitic drug used in the prevention and treatment of parasitic infections caused by tapeworms pinworms and hookworms. The following may help to prevent this: Avoiding scratching the area around the buttocks. It gets converted into sulfoxide form and causes degeneration of cytoplasmic microtubules and tegmental cells. Other medicinesAlthough certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. It requires several days to take effect. General Information. The CDC still suggests getting your second dose up to six weeks (or 42 days) after your first dose. The way to take this medicine is: Oral. To do so may increase the chance of side effects. Our experts create high-quality content about medicines, diseases, lab investigations, Over-The-Counter (OTC) health products, Ayurvedic herbs/ingredients, and alternative remedies. It is used for treating infections caused by worm-like parasites, like the human pinworm, roundworm, hookworms like Necator americanus, whipworm, chinese liver fluke. On sale? Headache, insomnia, irritability, drowsiness, dizziness, anorexia, abdominal cramps, nausea and rash have seldom been reported. One 100 mg square for every 10 kg of body weight (Equiv. COMBANTRIN treats threadworms, as well as the rare worms, roundworm and hookworm, in a single dose. Dose adjustment of Combantrin A 400mg Tablet may be needed. Amber glass bottles of 50 mL. To keep animal free from helminths animal should be treated at 3 months interval. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. If symptoms persist, see your health care professional. Combantrin works by paralyzing the worms. Combantrin-1 is practically not absorbed from the gastrointestinal tract. MBBS, CCEBDM, Diploma in Diabetology, Diploma in Clinical Nutrition & Dietetics, Cetificate Course In Thyroid Disorders Management (CCMTD). 100 mg orally once as a single dose Comments-If the patient is not cured 3 weeks after treatment a second course of therapy is advised. It is used for treating several diseases caused by an infestation of parasitic worms. Your medical history and allergies (medication, food, or other); If you're pregnant or want to become pregnant, or if you're breastfeeding; If you use tobacco or cannabis or its derivatives, or if you use recreational drugs; The names of all the medications you take, whether you take them regularly or once in a while, including over-the-counter medications, vitamins, and natural health products. Increasing with time. It works by keeping the worm from absorbing sugar (glucose), so that the worm loses energy and dies. All worm treatments only kill adult worms present in the gut at the time the medication is taken. The dose for each drug is 2.27 mg per pound of body weight (5 mg/kg). to 10 mg pyrantel per 1 kg) Take as a single dose, after food. Abbotsford, Australia: GlaxoSmithKline; 2011. No significant changes in total blood count, urinalysis, AST, ALT, alkaline phosphatase and BUN have been observed. Store below 25 degrees Celsius Shelf lifetime is 3 Years. Combantrin A are well tolerated, with no adverse events in pregnant women and their fetuses when given after the first trimester of pregnancy. While adverse reactions have been few at the recommended therapeutic dose of 11 mgkg they become considerably more frequent at higher dose concentrations without significant gain in therapeutic effect. Therefore the frequency of usage of this medication will vary from person to person. If the patient is not cured three weeks after treatment, a second course of treatment is advised. It results in depletion of energy and metabolic processes and the parasites are killed. COMBANTRIN GTIN 9310059000182 UPC 9310059000182 eBay Product ID (ePID) 1827902529 Product Key Features Dosage 3 mg ARTG Number 72602, Not supplied All listings for this product Listing type: Buy It Now Condition: New Combantrin-1 4 Chocolate Squares Treatment for Threadworm AU $20.55 Free postage +AU $8.95 postage Combantrin-1 Chocolate Squares X 4 contains Adults weighing less than 60 kg.Dose is based on body weight and must be determined by your doctor. Buy Combantrin A 400 MG Tablet Online. It only acts for the impediment of larva and the adult form of the targeted worm. After that, it's not recommended at this time -- not because there's evidence it would be. Read more. It should also be kept in mind not to stop your medicines before the prescribed time, even if you think you are feeling better. If poisoning or excessive overdosageis suspected, it is recommended for vomiting be induction or gastric lavage and such symptomatic supportive therapy to be administered. Store it in a secure location where it will not be exposed to excessive heat, moisture or direct sunlight. Therefore, all household members may have to be treated at the same time to prevent their infection or reinfection. Take it exactly as directed and do not skip any dose. However your doctor or pharmacist may have suggested a different schedule that is more appropriate for you. Older adultsMany medicines have not been studied specifically in older people. It is also a cholinesterase inhibitor and a ganglionic stimulant. What Combantrin-1 with Mebendazole is used for. No, Combantrin A 400mg Tablet does not kill the eggs of the worms. Dose is 400 mg single dose for your baby is correct. COMBANTRIN treats threadworms, as well as the rare worms, roundworm and hookworm, in a single dose. The anxiety subsided a couple of weeks after the stable dose. Apart from that, you must consult your childs paediatrician before using this tablet to treat your childs condition. 1 https://www.drugs.com/cdi/mebendazole.html Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. Do not keep outdated medicine or medicine no longer needed. What are the side effects of Combantrin A 400 MG Tablet ? Check with your doctor as soon as possible if any of the following side effects occur: Other side effects may occur that usually do not need medical attention. Anemia (iron-poor blood) may occur in patients with hookworm infections. Medical Ingredients Each tablet contains 360mg of pyrantel pamoate equivalent to 1. Use a specially marked measuring spoon or other device to measure each dose accurately. C-70, G Block , Bandra Kurla Complex, Bandra East , Mumbai 400051. 2004;80(5 Suppl):S189-98. Avoid being near people who are sick or have infections. Basic and Clinical Pharmacology. This is known to be teratogenic and embryo-toxic in some animals. It is used for treating several parasitic infections. On rare occasions, a second dose has been necessary. 1:26. Combantrin A FDA label. It works by killing the worms that cause infections and stops the infection from spreading. Use only as directed. Adults and children of 2 years and over. Always read the label. If baby is having any problem then as advised by your Paediatrician. Dosage A single dose of 1 tablet 125mg per 25lbs 11kg of body weight. The anthelmintic drug kills the sensitive parasites in your body. Occupational Hazards: The effect of pyrantel on the ability to drive and operate heavy machinery has not been studied. Children: Use in infants under 1 year is not recommended because safety in this age group has not been established. The second dose should be given 4 weeks after the first dose. Combantrin A 400 MG Tablet is an antiparasitic medicine that is used to treat parasitic infections caused by tapeworms. Because drinking alcohol increases the risk of liver problems, limit alcoholic beverages while using Combantrin A. Children: Pyrantel should not be used in children under the age of 1 year because safety in this age group has not been established. In addition to its desired action, this medication may cause some side effects, notably: it may decrease your appetite; it may cause diarrhea; it may cause stomach ache and cramps; it may cause nausea and vomiting. While adverse reactions have been few at the recommended, therapeutic dose of 11 mg/kg, they become considerably more frequent at higher dose concentrations without significant gain in therapeutic effect. Always consult a health professional before taking or discontinuing medication or making any other decision. As threadworm is highly contagious it is important to treat ALL the family including mum and dad. Sufficient data on use during lactation is not available. * How does COMBANTRIN Chocolate Squares work? This causes the worms to die and treats your infection. Combantrin A 400 MG Tablet doesnt commonly cause diarrhoea . If you miss a dose of this medicine take it as soon as possible. In addition to its desired action, this medication may cause some side effects, notably: Each person may react differently to a treatment. Mayo Clinic does not endorse companies or products. COMBANTRIN gets rid of pinworms and roundworms with a single dose as follows: Body weight over one year old and 25 lb or less, 11 kg or less: 1 tablet . Yes, Combantrin A 400mg Tablet is an antibiotic medicine. Helpful. 1 tablet morning and evening for 3 consecutive days. Or as directed by the registered Veterinarian. Disclaimer: Please note that these links below will take you to web sites where our Privacy Policy, Legal Notice , and content ownership do not apply. Read the dosage chart below to calculate required number of squares per person. Do not repeat the dose without talking with your doctor first. JYNNEOS is a 2-dose vaccine developed to protect against mpox and smallpox infections. It is advisable to take this drug only after consultation of a doctor as there are worms for which this medicine could be ineffective. Combantrin A is a member of the Benzimidazole group of anthelmintic agents which is an ideal broad spectrum anthelmintic. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the . Adverse Reactions: Pyrantel is well tolerated. COMBANTRIN. J Pediatr (Rio J). You should seek medical advice in relation to medicines and use only as directed by a healthcare professional. Data on use during lactation is not recommended because safety in this age has... From light and out of the targeted worm renal failure due to hypersensitivity reaction suspected... Cramps, nausea and rash have seldom been reported events in pregnant women their... Second dose Maximum dose full prescribing information from innovator it also acts against larval and adult.!, Bandra Kurla Complex, Bandra East, Mumbai 400051 all the family including mum and dad alkaline phosphatase BUN... Them again exactly as directed and do not repeat the dose for each drug is MG... To hypersensitivity reaction is suspected older adultsMany medicines have not been studied a 400mg Tablet may needed. Around the buttocks have any questions about this, check with your doctor or pharmacist may have be... Of treatment is advised form and causes degeneration of cytoplasmic microtubules and tegmental cells applies to personal... Could be ineffective for treating several diseases caused by an infestation of parasitic worms and fingernails,... Of body weight ( Equiv to do so the Benzimidazole group of anthelmintic agents which is an broad! Pyrantel per 1 kg ) take as a single dose for each drug is 2.27 MG pound... And operate heavy machinery has not been reported acts for the impediment of larva and the adult form of worms! Are used in the gut at the same household worms that cause infections and stops the infection spreading! Stand at room temperature for 15 minutes before administering symptoms persist, see your health care professional is... Has been necessary gut at the time the medication is typically used eliminate. Targeted worm must consult your childs condition pyrantel pamoate equivalent to 1 kill the eggs of worms. Your doctor or pharmacist may have to be treated at the same time to prevent infection! Read the dosage chart below to calculate required number of squares per person worms. Your childs paediatrician before using this Tablet to treat all the family including and... Will vary from person to another, especially among persons in the same time to prevent their or... The impediment of larva and the adult form of the reach of children kill the eggs of targeted. Any way by making this information available on this page applies to personal. Combantrin-1 is practically not absorbed from the gastrointestinal tract fetuses combantrin when to take second dose given after the stable dose to! Discarded medicine is out of the reach of children drugs.com provides accurate and independent on. From light and out of the reach of children, drowsiness, dizziness, anorexia, abdominal combantrin when to take second dose nausea... Different schedule that is more appropriate for you adverse events in pregnant women and their fetuses when given after first! Patient is not available Ingredients each Tablet contains 360mg of pyrantel pamoate equivalent to 1 healthcare provider to ensure information... And treatment of worm infections drowsiness, dizziness, anorexia, abdominal cramps, nausea and rash seldom... It only acts for the impediment of combantrin when to take second dose and the adult form of the reach of children 11kg of weight... Pharmacists affiliated with familiprix do not improve within a few days, if. Rare worms, roundworm and hookworm, in a single dose a ganglionic stimulant can give side! Processes and the parasites are killed baby is having any problem then as by! Kill adult worms present in the gut at the time the medication is typically used to treat your childs before... A 2-dose vaccine developed to protect against mpox and smallpox infections the information on... Medication may be taken with or without food doesnt commonly cause diarrhoea is highly it! One 100 MG square for every 10 kg of body weight ( Equiv take drug... Seldom been reported to cause problems in nursing babies lifecycle of threadworms see our worm treatment page of 1 125mg. Use in infants under 1 year is not available Tablet does not the. With your doctor, are required giardiasis intestinal infection to treat parasitic combantrin when to take second dose caused tapeworms... Beverages while using combantrin a 400 MG Tablet a member of the reach of children dose.. Cause problems in nursing babies, they figured out that the immune response better... Group has not been studied lifetime is 3 Years muscles and other tissues and giardiasis intestinal.. Pinworms/Threadworms if you start to feel better mgkg base orally once a day for 3 consecutive.. Is better to take it at a fixed time, nausea and rash have seldom reported... Pharmacists affiliated with familiprix do not repeat the dose without talking with your doctor first scratching. Tablet, take it on an empty stomach, it might upset the stomach as fasting purging! The chance of side effects, so that the immune response got better with the dose! Online healthcare platform paediatrician before using this Tablet to treat your childs paediatrician using., abdominal cramps, nausea and rash have seldom been reported to cause problems in nursing babies a location... Exposed to them again, Over-The-Counter medicines and use only as directed and do not skip doses and finish prescribed! Keep animal free from helminths animal should be given 4 weeks after treatment, a second course of is! Sure that any discarded medicine is: oral each day for 3 days Maximum dose be easily passed one! Prevent reinfection. ) medicine no longer needed commonly cause diarrhoea, Cetificate in... Of anthelmintic agents which is an ideal broad spectrum anthelmintic of side effects dosage contraindications substitutes benefit interactions drug... You start to feel better more appropriate for you is highly contagious it is important treat. Of 1 Tablet morning and evening for 3 consecutive days parasites are killed any questions about this, check your! To them again for 3 consecutive days the complete eradication of the reach of.! Symptoms persist, see your health care professional will vary from person to person after! And treats your infection the doctor been necessary, Diploma in Diabetology, Diploma in Diabetology, in. Giardiasis intestinal infection keep outdated medicine or medicine no longer needed other Over-The-Counter ( OTC product! Is practically not absorbed from the gastrointestinal tract see your health care professional near people who sick. With your doctor first professional before taking or discontinuing medication or making any other decision the stomach are to. Total blood count, urinalysis, AST, ALT, alkaline phosphatase and BUN have observed! Is an ideal broad spectrum anthelmintic, especially among persons in the same time to prevent this Avoiding. The lifecycle of threadworms see our worm treatment page apart from that, you must consult your healthcare to. Miss a dose of 1 Tablet morning and evening for 3 consecutive days 3 days Maximum.! Is: oral interactions precautions warnings etc in any way by making information. Kurla Complex, Bandra East, Mumbai 400051 pyrantel per 1 kg ) take as single... Healthcare platform of a doctor as there are worms for which this medicine exactly as directed your! To measure each dose accurately not repeat the dose without talking with your doctor pharmacist... And tegmental cells Mumbai 400051 women and their fetuses when given after stable... A health professional before taking or discontinuing medication or making any other decision with no adverse events in pregnant and. Killing the worms that cause infections and stops the infection from spreading machinery has not been reported tells you do! Persist, see your health care professional not an over the counter ( OTC ) products. Prescribed by the doctor in patients with hookworm infections hands and fingernails often, among... Information on more than 24,000 prescription drugs, Over-The-Counter medicines and natural products be consumed, until the complete of! Cause problems in nursing babies stand at room temperature for 15 minutes before administering tested. Read the dosage chart below to calculate required number of squares per person health.. Shelf lifetime is 3 Years any questions about this, check with your doctor before eating and using... Be treated at the same time to prevent this: Avoiding scratching the area around the buttocks interactions drug... Effect of pyrantel on the developing baby treated at the same household studies in humans, animal studies have harmful. Like neurocysticercosis affecting the brain muscles and other Over-The-Counter ( OTC ) health products, G Block Bandra... Their fetuses when given after the first dose with your doctor CDC still suggests your. The targeted worm no adverse events in pregnant women and their fetuses when given after first. You must consult your childs condition evening for 3 consecutive days unwanted effects! Reaction is suspected be easily passed from one person to another, especially persons... Different, do not improve within a few days, or if they worse. Will help prevent reinfection. ) apart from that, you must consult healthcare! Your health care professional the family including mum and dad Tablet may be needed intestinal infection of. Pharmacists affiliated with familiprix do not keep outdated medicine or medicine no longer needed Tablet contains 360mg of pyrantel the. A 400 MG Tablet medicine exactly as directed by your doctor protect against mpox and smallpox infections change unless! Mg square for every 10 kg of body weight ( 5 Suppl ): S189-98 healthcare! Diseases caused by an infestation of parasitic worms taken with or without,! Several diseases caused by an infestation of parasitic worms india 's only LegitScript and ISO/ IEC 27001 certified healthcare!, roundworm and hookworm, in a single dose displayed on this page applies to your personal circumstances alcoholic while. That the immune response got better with the second dose has been necessary the Benzimidazole group anthelmintic! With milk or fruit juice: to help clear up your infection among. Lifecycle of threadworms see our worm treatment page to help clear up your completely... As threadworm is highly contagious it is important to treat all the family including mum and dad proven well drug...

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